DEVELOPING A BIOINFORMATICS PROGRAM AND SUPPORTING INFRASTRUCTURE IN A BIOMEDICAL LIBRARY


From Heart Health Promotion to Chronic Disease Prevention: Contributions of the Canadian Heart Health Initiative

Background The Canadian Heart Health Initiative began in 1987 as an 18-year undertaking to address the epidemic of cardiovascular disease in Canada.There is growing recognition in Canada of the need for an integrated approach to prevention that addresses common risks for many chronic diseases.Context Research and intervention activities of the Cana

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Nutritional regulation of cholesterol synthesis and apolipoprotein B kinetics: studies in patients with familial hypercholesterolemia and normal subjects treated with a high carbohydrate, low fat diet.

High carbohydrate, low fat diets decrease plasma low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB) mass in normal subjects and in patients with familial hypercholesterolemia (FH).To investigate the mechanisms for these effects, four normal, four FH heterozygous, and one FH homozygous subjects were studied on a basal (45% carbo

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Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas

Abstract Background Members of the PDGF family have been suggested as potential biomarkers for papillary thyroid carcinomas (PTC).However, it is known that both expression and stimulatory effect of PDGF ligands can be affected by inflammatory cytokines.We have performed a microarray study in a collection of PTCs, of which about half the biopsies co

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